Explore

your

genetic

predisposition

for

addiction.

Explore your genetic predisposition for addiction.

Addiction Profiler helps you understand your genetic risk for opioid dependence, alcohol consumption, alcohol dependence, and cannabis use disorder using your DNA.

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How it works.

Download your Raw DNA File

Traitwell Addiction App supports raw data files from 23andMe, Ancestry, and FamilyTreeDNA.

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Get your raw DNA data file:

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"Family studies that include identical twins, fraternal twins, adoptees, and siblings suggest that as much as half of a person's risk of becoming addicted to nicotine, alcohol, or other drugs depends on his or her genetic makeup"

“Genetics: The Blueprint of Health and Disease” - National Institute on Drug Abuse

Understand your risk for addiction.

Find out how likely you are to become an addict and learn what genes could increase the chances of drugs or alcohol addiction. Discover your genetic traits for different types of addiction, including the tendency for dependency on alcohol and drugs.

Find out if you or your loved ones are at risk.

Addiction can be inherited. Find out if you or a loved one are at risk for substance addiction by taking the first step to understanding the genetic predisposition for various types of addiction. Knowing your genetic traits can help you take the right steps forward.

A new kind of addiction profile app.

Take a look inside yourself by using our app to learn about your genetic predisposition for addiction. It’s free and secure.

“The past few years have seen remarkable progress in our understanding of the genetics, and therefore the biology, of substance use and abuse.”

“Genetics of substance use disorders in the era of big data” - Nature Reviews Genetics

Based on the latest research.

“Twin resemblance for sedative, stimulant, cocaine, and opiate use, however, was caused solely by genetic factors. With 2 exceptions (cocaine abuse and stimulant dependence), twin resemblance for heavy use, abuse, and dependence resulted from only genetic factors, with heritability of liability usually ranging from 60% to 80%.”

Kendler KS, Karkowski LM, Neale MC, Prescott CA. “Illicit Psychoactive Substance Use, Heavy Use, Abuse, and Dependence in a US Population-Based Sample of Male Twins.” Arch Gen Psychiatry vol.57,3 (2000):2 61–269. doi:10.1001/archpsyc.57.3.261

“Understanding the biology of human responses to opioids may lead to effective preventive strategies and treatments to reduce [opioid dependence] and its harmful consequences. Human genetic research has the potential to dissect the basis of inter-individual variability in the response to opioid exposure (i.e., whether an individual develops dependence on opioids).”

Polimanti, Renato et al. “Leveraging genome-wide data to investigate differences between opioid use vs. opioid dependence in 41,176 individuals from the Psychiatric Genomics Consortium.” Molecular psychiatry vol. 25,8 (2020): 1673-1687. doi:10.1038/s41380

Alcohol dependence (AD) is moderately heritable (49% by a recent meta-analysis) and numerous genome-wide association studies (GWAS) have aimed to identify loci contributing to this genetic variance … According to one study, common SNPs are responsible for as much as 30% of the variance in AD … Variants in the genes responsible for alcohol metabolism, especially ADH1B and ALDH2, have been strongly implicated.”

Walters, Raymond K et al. “Transancestral GWAS of alcohol dependence reveals common genetic underpinnings with psychiatric disorders.” Nature neurosciencevol. 21,12 (2018): 1656-1669. doi:10.1038/s41593-018-0275-1

Your DNA is not your destiny.

Find out if you have an increased genetic risk for addiction, and then use what you learn to live a healthier life

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DISCLAIMER: This is a general health and wellness application and is not intended to diagnose or treat substance addiction. This application simply provides risk scores based on your unique characteristics while integrating the latest genomics research. Our algorithms are living and breathing, constantly being updated based on the latest evidence. Please discuss your actual risk for substance addiction with your personal physician.